GENOME RESEARCH

Launched in 1995, Genome Research is an international, continuously published, peer-reviewed journal that publishes studies on the structure, function, biology, and evolution of genomes of all organisms, with a long-standing emphasis on genome-scale analyses, chromatin structure and function, epigenomics, systems genetics, and proteomics. We also feature gene discoveries that provide novel insights and reports of high-throughput experimental and computational approaches. In addition to these core areas, the journal is now particularly interested in the following areas:comprehensive characterization of genome sequence variationunderstanding the basis of phenotypic complexitynetwork biology and the functional effects of genetic variationevolutionary mechanisms of species origin, adaptation, and genomic diversity, including the study of ancient DNAgenomic medicine, including mechanisms of penetrance, expressivity, and modifier effectsunderstanding genomic and biological processes through single-cell analysesnovel computational algorithms that provide insight into biological processesgenome editing and engineering

基因组研究(Genome Research)成立于1995年，是一份国际性的、连续出版的、同行评议的期刊，发表关于所有生物体基因组的结构、功能、生物学和进化的研究，长期以来一直强调基因组规模分析、染色质结构和功能、表观基因组学、系统遗传学和蛋白质组学。我们还以基因发现为特色，为高通量的实验和计算方法提供新的见解和报告。除这些核心领域外，《日刊》现在对下列领域特别感兴趣:基因组序列变异的综合表征理解表型复杂性的基础网络生物学与遗传变异的功能效应物种起源、适应和基因组多样性的进化机制，包括对古代DNA的研究基因组医学，包括外显率、表达和修饰效应的机制通过单细胞分析了解基因组和生物学过程提供深入了解生物过程的新型计算算法基因组编辑与工程