DIFFERENTIATION

Differentiation is a multidisciplinary journal dealing with topics relating to cell differentiation, development, cellular structure and function, and cancer. Differentiation of eukaryotes at the molecular level and the use of transgenic and targeted mutagenesis approaches to problems of differentiation are of particular interest to the journal.The journal will publish full-length articles containing original work in any of these areas. We will also publish reviews and commentaries on topics of current interest.The principal subject areas the journal covers are: ? embryonic patterning and organogenesis? human development and congenital malformation? mechanisms of cell lineage commitment? tissue homeostasis and oncogenic transformation? establishment of cellular polarity? stem cell differentiation? cell reprogramming mechanisms? stability of the differentiated state? cell and tissue interactions in vivo and in vitro? signal transduction pathways in development and differentiation? carcinogenesis and cancer? mechanisms involved in cell growth and division especially relating to cancer? differentiation in regeneration and ageing? therapeutic applications of differentiation processes

《分化》是一本多学科期刊，涉及细胞分化、发育、细胞结构和功能以及癌症等主题。在分子水平上的真核生物分化，以及利用转基因和定向诱变方法来解决分化问题是该杂志特别感兴趣的。该杂志将发表包含上述任何领域原创作品的全文文章。我们亦会就当前感兴趣的课题发表评论。该杂志涵盖的主要主题领域是:?胚胎模式和器官形成?人类发展和先天畸形?细胞谱系承诺机制?组织稳态和致癌转化?细胞极性的建立?干细胞分化?细胞重编程机制?差异化状态的稳定性?细胞和组织在体内和体外的相互作用?发育和分化中的信号转导通路?致癌和癌症?参与细胞生长和分裂的机制，特别是与癌症有关的?再生和衰老的分化?分化过程的治疗应用