BIOPOLYMERS

Biopolymers publishes original research papers and review articles in the general area of macromolecular structure and function, as well as biologically relevant model systems. Manuscripts should report on studies that examine biological macromolecules (naturally occurring and designed), their interactions, reactions, and macromolecular assemblies at structural, chemical, and physical levels. The Journal strives to publish high-impact papers that will significantly enhance our understanding of the chemistry and/or the biology of the systems under investigation. Reports describing techniques that could be applied to the study of biological macromolecules will be considered for publication only if they will have broad utility to the biochemical and biophysical research community.Topics of particular interest include, but are not limited to:Molecular recognition; multi-component complexes and macromolecular assembly, including ordered aggregationMolecular design, biomimics, model systems, and bio-nanotechnologyBiopolymer processing and degradationExperimental and theoretical studies of biopolymer foldingSingle molecule studies of biopolymers (e.g., fluorescence, optical tweezers, AFM, etc.)Three-dimensional structures of biopolymers determined by X-ray, NMR, EM, other spectroscopic methods, as well as computational predictionBioenergetics of macromolecules and their interactionsUse of small molecules as either probes or models of structure and function, or as ligands that target biologically relevant receptorsPreparation and characterization of novel biomaterialsFunction may include:DNA recombination, replication and repairCatalysisMolecular motorsIntracellular signaling and signal transductionChromatin structure and remodelingRNA processingTranscriptionTranslationProtein/RNA sorting and trafficking

生物聚合物在大分子结构和功能以及生物相关的模型系统的一般领域发表原始的研究论文和评论文章。手稿应报告研究生物大分子(自然发生和设计)，他们的相互作用，反应，和大分子组装在结构，化学和物理水平。该杂志致力于发表高影响力的论文，将显著提高我们对所研究系统的化学和/或生物学的理解。描述可应用于生物大分子研究的技术的报告只有在对生物化学和生物物理研究领域具有广泛用途时才会考虑发表。特别感兴趣的题目包括但不限于:分子识别;多组分配合物和大分子组装，包括有序聚集分子设计，仿生学，模型系统，生物纳米技术生物聚合物的加工和降解生物高分子折叠的实验与理论研究生物聚合物的单分子研究(如荧光、光镊、AFM等)生物聚合物的三维结构由x射线、NMR、EM等光谱方法测定，以及计算预测大分子的生物能学及其相互作用利用小分子作为探针或结构和功能的模型，或作为靶向生物学相关受体的配体新型生物材料的制备与表征功能可能包括:DNA重组，复制和修复催化分子马达细胞内信号和信号转导染色质结构和重塑RNA加工转录翻译蛋白质/RNA的分类和运输