CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacology & Therapeutics (CPT) is the authoritative cross-disciplinary journal in experimental and clinical medicine devoted to publishing advances in the nature, action, efficacy, and evaluation of therapeutics. CPT welcomes original articles, letters and communications in the emerging areas of translational, predictive and personalized medicine; new therapeutic modalities including gene and cell therapies; pharmacogenomics, proteomics and metabolomics; bioinformation and applied systems biology complementing areas of pharmacokinetics and pharmacodynamics, human investigation and clinical trials, pharmacovigilence, pharmacoepidemiology, pharmacometrics, and population pharmacology. Commentaries and Point-Counterpoint provide a forum for perspectives in clinical pharmacology and therapeutics in the context of contemporary scientific, political, economic and social issues. State of the Art contributions summarize the latest advances in the science underpinning drug discovery, development, regulation and utilization. CPT highlights issues transforming the practice of clinical pharmacology, including ethics, education and public policy. Bench-to-bedside translation in therapeutics is presented in the context of clinical applications of basic pharmacology, discovery and translational medicine, and drug development.

临床药理学与治疗学(CPT)是实验医学和临床医学的权威交叉学科期刊，致力于发表治疗学的性质、作用、疗效和评价方面的进展。CPT欢迎翻译、预测和个性化医学新兴领域的原创文章、信函和通信;新的治疗方式包括基因和细胞疗法;药物基因组学、蛋白质组学和代谢组学;生物信息和应用系统生物学补充药物动力学和药效学、人体调查和临床试验、药物警戒、药物流行病学、药物计量学和人口药理学等领域。评论和观点对位提供了一个论坛的观点，临床药理学和治疗在当代科学，政治，经济和社会问题的背景下。《最新进展》综述了支持药物发现、开发、管理和利用的科学方面的最新进展。CPT强调转变临床药理学实践的问题，包括伦理、教育和公共政策。在临床应用的基础药理学，发现和翻译医学，以及药物开发的背景下，治疗的基准到床边翻译。