BIOPHARMACEUTICS & DRUG DISPOSITION

The Journal publishes original reports of studies in biopharmaceutics drug disposition and pharmacokinetics especially those which have a direct relation to the therapeutic use of drugs. This includes human pharmacological studies and therapeutic response and toxicity related to plasma and tissue concentrations of drugs and their metabolites. Research on factors affecting the disposition of the clinical response to drugs and on the design of drug dosage regimens and the treatment of overdose based on pharmacokinetic principles are accepted. Papers on analytical methodology in vitro drug metabolism and on animal models are also published provided that either they facilitate the preceding types of investigation or they are related to the use of drugs in man. The Journal also publishes review articles

该杂志发表了生物药剂学、药物配置和药代动力学研究的原始报告，特别是那些与药物治疗使用直接相关的研究。这包括人类药理学研究和治疗反应以及与血浆和组织浓度相关的药物及其代谢产物的毒性。对影响药物临床反应处置的因素的研究，以及基于药代动力学原理的药物剂量方案的设计和过量治疗的研究均被接受。此外，还发表了关于体外药物代谢分析方法和动物模型的论文，只要这些论文有助于上述类型的研究，或者它们与人类药物的使用有关。该杂志还发表评论文章。