ONCOLOGY

Although laboratory and clinical cancer research need to be closely linked, ob?servations at the basic level often remain removed from medical applications. This journal works to accelerate the translation of experimental results into the clinic, and back again into the laboratory for further investigation. The fundamental purpose of this effort is to advance clinically-relevant knowledge of cancer, and improve the outcome of prevention, diagnosis and treatment of malignant disease. The journal publishes significant clinical studies from cancer programs around the world, along with important translational laboratory findings, mini-reviews (invited and submitted) and in-depth discussions of evolving and controversial topics in the oncology arena. A unique feature of the journal is a section which focuses on rapid peer-review and subsequent publication of short reports of phase 1 and phase 2 clinical cancer trials, with a goal of insuring that high-quality clinical cancer research quickly enters the public domain, regardless of the trial’s ultimate conclusions regarding efficacy or toxicity.

尽管实验室和临床癌症研究需要紧密联系，但在基础水平的观察常常被排除在医学应用之外。该期刊致力于加快实验结果的临床转化，并再次回到实验室进行进一步的研究。这项工作的根本目的是提高对癌症的临床相关知识，提高对恶性疾病的预防、诊断和治疗的结果。该杂志发表了来自世界各地癌症项目的重要临床研究，以及重要的转化实验室发现、微型评论(邀请并提交)和深入讨论肿瘤学领域不断发展和有争议的话题。杂志的一个独特的特性是一个专注于快速的部分同行评议和随后出版短篇报告阶段1和阶段2的癌症临床试验,确保高质量的临床癌症研究的目标迅速进入公共领域,无论关于功效和毒性试验的最终结论。