MOLECULAR CARCINOGENESIS

Molecular Carcinogenesis presents information describing investigations of molecular aspects of the mechanisms involved in chemical, physical, and viral (biological) carcinogenesis. Areas of interest include, but are not limited to, the structure, expression, or function of genes or gene products associated with normal growth and differentiation and alterations in neoplasia; characterization of genes or gene products expressed in preneoplastic or neoplastic cells; molecular studies that define a specific function of a tumor-associated protein or its effects on cellular function; virtually all research on molecular aspects of oncogenes, tumor suppressor genes, and their gene products; carcinogenesis studies in transgenic mice; and research on human tumor viruses.

分子癌变介绍了对化学、物理和病毒(生物)癌变机制的分子方面的研究。感兴趣的领域包括但不限于与肿瘤正常生长、分化和改变相关的基因或基因产物的结构、表达或功能;肿瘤前或肿瘤细胞中表达的基因或基因产物的表征;定义肿瘤相关蛋白的特定功能或其对细胞功能的影响的分子研究;几乎所有关于致癌基因、抑癌基因及其基因产物的分子方面的研究;转基因小鼠的致癌研究以及人类肿瘤病毒的研究。