JOURNAL OF MEDICINAL CHEMISTRY

The Journal of Medicinal Chemistry publishes original research on the correlation of molecular structure to biological activity with a focus on the relationships of chemistry to biological activity. This includes design and synthesis of novel biologically active compounds, molecular modifications designed to target drugs to specific tissues, the role of metabolism in drug actions, application of NMR and X-ray crystallography to investigate molecular recognition at receptors, molecular modeling studies that furnish fresh insight into the design of novel agents, and molecular biology studies to study the interaction of ligands and receptors. In addition to the rapid publication of research findings, this renowned journal also publishes a Perspective series devoted to a single research topic, communications, brief articles, and extensive book review sections.

《药物化学杂志》发表了关于分子结构与生物活性相关性的原创研究，重点关注化学与生物活性之间的关系。这包括设计和合成新颖的具有生物活性的化合物,分子设计修改目标药物到特定的组织,在药物代谢行为的作用,应用核磁共振和x射线晶体学研究分子识别受体,分子建模研究提供新的见解新颖的代理的设计,和分子生物学研究,研究配体和受体之间的相互作用。除了快速出版研究成果，这本著名的杂志还出版了一个视角系列，致力于一个单一的研究主题，沟通，简短的文章，和广泛的书评部分。