JOURNAL OF APPLIED TOXICOLOGY

The Journal of Applied Toxicology is devoted to publishing original research theoretical and literature reviews relating to the toxicity of drugs and chemicals to living systems at the molecular cellular tissue and target organ level. This also encompasses teratogenesis carcinogenesis mutagenesis mechanistic technology pharmacokinetics environmental toxicology and environmental health (including epidemiological studies) in addition to analytical and method development studies. Papers dealing with in vitro techniques and alternatives to the use of animals are encouraged. Experiments on animals should conform to prevailing national or international standards of welfare care and handling of animals (eg NUH guidelines). Investigations in human volunteers and patients must indicate that relevant ethical reviews and guidelines have been followed including obtaining informed consent. Papers must be of clear scientific value and contribute to knowledge and advancement in toxicology. All papers will be independently refereed. Contributions must be in English and not have been published elsewhere except as abstracts at scientific meetings. Review articles will be published and prior consultation with one of the editors is reommended. Review articles will also be refereed. Authors must agree not to communicate the same material for publication elsewhere.

《应用毒理学杂志》致力于在分子细胞组织和靶器官水平上发表有关药物和化学品对生物系统毒性的原始研究理论和文献综述。这也包括致畸、致癌、突变、机械技术、药代动力学、环境毒理学和环境卫生（包括流行病学研究）以及分析和方法开发研究。鼓励发表有关体外技术和动物使用替代方法的论文。动物实验应符合现行的国家或国际动物福利护理和处理标准（如NUH指南）。对人体志愿者和患者的调查必须表明，已经遵循了相关的伦理审查和指导方针，包括获得知情权。论文必须具有明确的科学价值，有助于毒理学的知识和进步。所有的论文都将被独立引用。稿件必须用英语书写，除作为科学会议的摘要外，不得在其他地方发表。将发表评论文章，并重新征求其中一位编辑的意见。评论文章也将被引用。作者必须同意不将同一材料传播到其他地方出版。