ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Environmental Toxicology and Pharmacology publishes the results of studies concerning toxic and pharmacological effects of (human and veterinary) drugs and of environmental contaminants in animals and man.Areas of special interest are: molecular mechanisms of toxicity, biotransformation and toxicokinetics (including toxicokinetic modelling), molecular, biochemical and physiological mechanisms explaining differences in sensitivity between species and individuals, the characterisation of pathophysiological models and mechanisms involved in the development of effects and the identification of biological markers that can be used to study exposure and effects in man and animals. In addition to full length papers, short communications, full-length reviews and mini-reviews, Environmental Toxicology and Pharmacology will publish in depth assessments of special problem areas. The latter publications may exceed the length of a full length paper three to fourfold. A basic requirement is that the assessments are made under the auspices of international groups of leading experts in the fields concerned. The information examined may either consist of data that were already published, or of new data that were obtained within the framework of collaborative research programmes. Provision is also made for the acceptance of minireviews on (classes of) compounds, toxicities or mechanisms, debating recent advances in rapidly developing fields that fall within the scope of the journal.The table of contents for this journal is now available pre-publication, via e-mail, as part of the free ContentsDirect service from Elsevier Science. Please send an e-mail message to cdhelp@elsevier.co.uk for further information about this service.

环境毒理学和药理学发表关于(人类和兽医)药物的毒性和药理作用以及动物和人的环境污染物的研究结果。特别感兴趣的是：毒性的分子机制，生物转化和毒代动力学（包括毒代动力学模型），分子、生化和生理机制解释了物种和个体之间敏感性的差异，病理生理模型的特征和涉及效果发展的机制以及可用于研究人和动物暴露和影响的生物标志物的鉴定。除了长篇论文、简短通讯、长篇评论和小型评论外，环境毒理学和药理学还将发表对特殊问题领域的深入评估。后一种出版物的篇幅可超过一篇完整论文的三至四倍。一项基本要求是在有关领域主要专家的国际小组主持下进行评估。所审查的资料可以是已经发表的数据，也可以是在合作研究方案框架内取得的新数据。所列经费还用于接受关于(类)化合物、毒性或机理的小型审查，辩论属于该期刊范围内的迅速发展领域的最新进展。该期刊的目录现在可以通过电子邮件提前发布，作为埃尔塞维尔科学的免费内容直接服务的一部分。请发电子邮件给cdhelp@elsevier.co.uk，了解有关这项服务的更多信息。